I-Vilazodone iyi-antidepressant esetshenziselwa ukwelapha ukuphazamiseka kokucindezeleka kubantu abadala. Isebenza ohlelweni lwezinzwa olumaphakathi, ikhulisa amazinga e-serotonin ebuchosheni, esiza ukuthuthukisa imizwa futhi inciphise izimpawu zokudangala. I-Vilazodone ingase futhi iboniswe ekwelapheni ukuphazamiseka kokukhathazeka okujwayelekile.
Njengayo yonke imithi, i-Vilazodone ingabangela imiphumela emibi, njengokucanuzela kwenhliziyo, isifo sohudo, umlomo owomile, ukuqwasha, isiyezi, nobuhlungu bekhanda. Kubalulekile ukuqaphela ukuthi, kwezinye izimo, i-Vilazodone ingandisa ingozi yemicabango yokuzibulala, ikakhulukazi ezigulini ezincane. Ngakho-ke, kubalulekile ukuthi lo muthi usetshenziswe ngaphansi kokugadwa uchwepheshe wezokunakekelwa kwezempilo oqeqeshiwe, ongaqapha imiphumela engemihle futhi alungise umthamo njengoba kudingeka.
Izinzuzo nezinkomba zokusebenzisa i-Vilazodone: uyini lo muthi?
I-Vilazodone isidakamizwa se-antidepressant esisetshenziselwa ukwelapha ukucindezeleka kubantu abadala. Le mithi isebenza ohlelweni lwezinzwa oluphakathi, isiza ukubuyisela ukulingana kwamakhemikhali obuchopho aphethwe yi-dysregulated kubantu abanokucindezeleka.
Izinzuzo ze-Vilazodone zihlanganisa ukuthuthukisa izimpawu zokucindezeleka, njengokudabuka okuqhubekayo, ukungabi nandaba nemisebenzi eyayijatshulelwa ngaphambili, izinguquko ebuthongweni kanye nesifiso sokudla, ukukhathala, nemizwa yokuphelelwa ithemba. I-Vilazodone ingase futhi iboniswe ekwelapheni ukuphazamiseka kokukhathazeka, njenge-generalized disorder disorder.
Kubalulekile ukugcizelela ukuthi i-Vilazodone kufanele isetshenziswe kuphela ngaphansi kwencwadi kadokotela, njengoba ukusetshenziswa ngendlela engafanele kungabangela imiphumela emibi engadingeki. Eminye yemiphumela engemihle evamile ihlanganisa isicanucanu, isiyezi, umlomo owomile, ukuqwasha, ukozela, ukujuluka, nokuqunjelwa.
Nokho, kubalulekile ukulandela iseluleko sezokwelapha futhi ubike noma yimiphi imiphumela engemihle engase ivele ngesikhathi sokwelashwa.
Iyini i-anxiolytic enezehlakalo eziphansi kakhulu zemiphumela emibi?
I-Vilazodone a antidepressant okuyingxenye yekilasi lama-serotonin reuptake inhibitors akhethiwe kanye nama-serotonin receptor antagonists. Lo muthi usetshenziswa ekwelapheni ukudana kubantu abadala.
Ngokuphathelene nemiphumela emibi, i-Vilazodone iye yahlotshaniswa nesigameko esiphansi se- imiphumela emibi uma uqhathaniswa nabanye i-anxiolyticsEminye yemiphumela emibi evame kakhulu ihlanganisa isicanucanu, isifo sohudo, ukuqwasha, kanye nekhanda elibuhlungu.
Kubalulekile ukugcizelela ukuthi isiguli ngasinye singasabela ngendlela ehlukile emuthini, futhi kubalulekile ukulandela imiyalelo kadokotela. Ngaphezu kwalokho, kubalulekile ukubika noma yiziphi izimpawu ezingajwayelekile kumhlinzeki wakho wokunakekelwa kwezempilo ukuze azihlole kanye nanoma yiziphi izinguquko ezidingekayo ekwelashweni kwakho.
Kodwa-ke, kubalulekile ukuthi uhlale uthintana nodokotela ngaphambi kokuqala noma yikuphi ukwelashwa ngalo muthi.
Imiphumela emibi yokusetshenziswa kwe-antidepressant: yiziphi izinkinga ezingase ziphakame?
Ama-antidepressants ayimithi esetshenziswa kakhulu ukwelapha ukuphazamiseka kwemizwelo njengokucindezeleka. Nokho, kubalulekile ukuqaphela imiphumela engemihle engase ivele ngesikhathi sokusetshenziswa kwayo, kuhlanganise naleyo ehlotshaniswa ne-Vilazodone, i-antidepressant evame ukunikezwa.
Eminye yemiphumela evame kakhulu ye-Vilazodone ihlanganisa isicanucanu, isiyezi, ukukhathala, umlomo owomile, nokuqunjelwa. Lezi zimpawu ngokuvamile ziba mnene futhi zivame ukunyamalala njengoba umzimba ujwayela umuthi, kodwa kwezinye izimo, zingaphikelela futhi zidale ukungakhululeki.
Ngaphezu kwemiphumela emibi emincane, ukusetshenziswa kwe-Vilazodone kungase futhi kuhlotshaniswe nezinkinga ezinkulu kakhulu, njenge i-syndrome i-serotonergic, isimo esingavamile kodwa esingase sibulale esenzeka lapho kuneqile serotonin emzimbeni. Izimpawu ze-serotonin syndrome zihlanganisa ukudideka, ukuyaluza, ukujuluka, ukuthuthumela, ngisho nokuquleka. Kubalulekile ukufuna usizo lwezokwelapha ngokushesha uma kuvela noma yiziphi zalezi zimpawu.
Eminye imiphumela emibi engavamile ye-Vilazodone ihlanganisa i-syndrome kubi i-neuroleptic, hyponatremia e isandiso do isikhawu QT, okungaba nemiphumela emibi kakhulu empilweni yesiguli. Ngakho-ke, kubalulekile ukuqaphela noma yiziphi izimpawu eziyisixwayiso futhi uzibike ngokushesha kudokotela ohambelayo.
Ukuqapha ngokucophelela ukusabela komzimba wakho emuthini kanye nokubika noma yiziphi izimpawu ezingajwayelekile kudokotela wakho kuyizinyathelo ezibalulekile zokuqinisekisa ukuphepha nokusebenza ngempumelelo kokwelashwa.
Ama-antidepressants anezigameko eziphansi kakhulu zemiphumela emibi: yiziphi ezinconywa kakhulu?
Ama-Antidepressants yimithi esetshenziselwa ukwelapha ukuphazamiseka kwengqondo okuhlukahlukene, njengokucindezeleka nokukhathazeka. Nokho, eminingi yale mithi ingabangela uhla lwemiphumela emibi engadingeki. Ngakho-ke, kubalulekile ukubheka izinketho ezinezigameko eziphansi zale miphumela emibi.
Enye yemithi edambisa ukucindezeleka okuhlonzwe njengenengozi ephansi yemiphumela engemihle i-Vilazodone. Lo muthi usebenza ebuchosheni ukuze ulawule amazinga e-serotonin, i-neurotransmitter enesibopho sokulawula imizwa nemizwelo. Ngenxa yokuthi isebenza ngokuqondile, i-Vilazodone ijwayele ukudala imiphumela emibi embalwa kunamanye ama-antidepressants avamile emakethe.
Eminye yemiphumela emibi kakhulu ye-Vilazodone ihlanganisa isicanucanu, ikhanda elibuhlungu, nokuqwasha. Nokho, le miphumela ivamise ukuba mnene futhi ibe yesikhashana, ayiphazamisi kakhulu ukwelashwa. Ngaphezu kwalokho, i-Vilazodone nayo iboniswe ukuthi iyasebenza ekulawuleni izimpawu zokucindezeleka nokukhathazeka, okwenza kube inketho ekhangayo ezigulini eziningi.
Ngakho-ke, uma ufuna i-antidepressant enezinga eliphansi lemiphumela emibi, i-Vilazodone ingaba inketho enhle kakhulu ongayicabangela. Hlala uthintana nochwepheshe ukuze uthole ukwelashwa okungcono kakhulu kwecala lakho futhi uqinisekise ukuthuthuka okuphawulekayo kukhwalithi yakho yempilo.
Ukusetshenziswa kwe-Vilazodone (i-antidepressant) nemiphumela emibi
Esinye sezici zokwelapha ngemithi ukuthi azisebenzi ngendlela efanayo kuzo zonke iziguli. Ngakho-ke isidingo semithi enhlobonhlobo engalungiselelwa izidingo ezithile zomuntu ngamunye.
Endabeni yama-antidepressants, i- i-vilazodone ingenye yezidakamizwa ezifakwe ezinhlobonhlobo zemithi Kunemithi eminingana etholakalayo yokulwa nokucindezeleka. Kulesi sihloko, sizohlaziya izici zabo, indlela yokuphatha, imiphumela emibi engenzeka, kanye nezinyathelo zokuphepha okufanele uzithathe ngesikhathi sokusetshenziswa.
Iyini i-vilazodone?
I-Vilazodone, eyaziwa ngokuthi i-Viibryd, i isidakamizwa esidambisa ukucindezeleka esakhiwe futhi sakhangiswa e-United States kusukela ngo-2011 , ngenkathi ivunywa yi-American Food and Drug Administration (FDA).
Lo muthi, ovunyelwe ukusetshenziswa ekwelapheni ukucindezeleka okukhulu, ubonakala ngenhlanganisela ye-serotonin reuptake inhibitor (SSRI) ekhethiwe, i-serotonin receptor agonist, kanye ne-buspirone, i-anxiolytic agent ethuthukisa imiphumela ye-SSRIs.
I-Vilazodone isebenza ngokusiza ukubuyisela ukulingana kwezinto eziningana zobuchopho, kuhlanganise nokwandisa inani le-serotonin ebuchosheni. Ngenxa yalokho, Lo muthi we-antidepressant usiza ukugcina ibhalansi yengqondo .
Ngokufanayo, eminye yemiphumela eyinhloko i-vilazodone enayo empilweni yengqondo yomuntu ihlanganisa ukuthuthukisa isimo sengqondo, ukugqugquzela ukulawulwa nokuthuthukiswa kwemijikelezo yokulala, ukwandisa isifiso sokudla kanye namazinga wamandla, futhi ekugcineni, kungasiza ukubuyisela isithakazelo somuntu emisebenzini yansuku zonke.
Okokugcina, izifundo ngokusebenza kahle kwalo muthi azizange zibonise imiphumela ethanda i-vilazodone ngaphezu kwezinye izinhlobo zemithi yokucindezeleka; ngakho-ke, ukuphathwa kwayo noma incwadi kadokotela kungaphansi kokuthandwa nguchwepheshe ochazayo.
Isetshenziswa kuziphi izimo?
Njengoba kushiwo ephuzwini eledlule, i-vilazodone isetshenziswa njenge enye yezidakamizwa ezikhethwayo ekwelapheni ukucindezeleka okukhulu kanye ne-depressive syndromes Lezi zinkinga zibonakala ngokuba ukuphazamiseka kwengqondo noma kwengqondo lapho umuntu ezwa imizwa engemihle nedabukisayo ngendlela engapheli nebuhlungu.
Ezimweni eziningi, izimpawu ezingokomzwelo zokucindezeleka zihambisana nokuzethemba okuphansi, ukuncipha noma ukulahlekelwa isithakazelo emisebenzini noma imisebenzi eyayivuselela noma ekhangayo ngaphambili, ukuncipha kwamandla kanye nomuzwa wokukhathala okuqhubekayo, futhi ekugcineni, ukuzwa ubuhlungu obungokomzimba ngaphandle kwesizathu esibonakalayo, njengobuhlungu besisu.
Izifo ezicindezelayo, kanye nama-syndromes noma izimo ezinezimpawu ezicindezelayo, zingaba isithiyo ekuphileni kwansuku zonke kwesiguli, ziphazamise imisebenzi yazo yansuku zonke, ziguqule imikhuba yazo, kanye nemikhuba yazo yokudla, imijikelezo yokulala kanye nempilo evamile. Uma zingelashwa, izimpawu zingaba zimbi kakhulu kangangokuthi phakathi kuka-2 no-7% wabantu abanokucindezeleka baphendukela ekuzibulaleni njengendlela yokuqeda ukuhlupheka ababhekana nakho.
Iphathwa kanjani?
I-Vilazodone Ithengiswa ngendlela yethebhulethi ukuze iphathwe ngomlomo . Umthamo ojwayelekile walo muthi ithebhulethi eyodwa ngosuku, ehlala ithathwa ngesikhathi esifanayo futhi okungcono ngokudla.
Nokho, lezi izincomo zokuphatha jikelele. Ngokuvamile, uchwepheshe wezokwelapha uzolungisa umthamo wokwelashwa ngokwezidingo zesiguli , okumele ilandele imiyalelo ye- isiguli Lokhu kusho ukuthi ngaphansi kwezimo akumele isiguli siguqule umthamo onconyiwe we-vilazodone, ngokweqile noma ngokuzenzakalelayo.
Njengoba i-vilazodone ingeyesigaba semithi yengqondo, kungenzeka kakhulu ukuthi ukwelashwa kuzoqala kancane kancane, kuqala ngemithamo emincane ezokwanda emasontweni ambalwa okuqala okwelashwa.
Imiphumela ye-vilazodone ingathatha amasonto ayisishiyagalombili ukuze ibonwe isiguli; ngakho-ke, uma isiguli singathuthuki noma sibona imiphumela emibi, isiguli Akufanele uyeke ukuphuza umuthi noma ushintshe umthamo ngaphandle kokubonisana nodokotela wakho kuqala. . Imiphumela ehlotshaniswa nokuhoxiswa kwe-vilazodone kungazelelwe ingase ihlanganise ikhanda elibuhlungu, ukuphazamiseka kwemizwelo, ukuqhuma okukhulu kwentukuthelo, isiyezi, ukuyaluza, ukwanda kokujuluka, noma ukuquleka, phakathi kokunye okuningi.
Imiphi imiphumela emibi enayo?
Njenganoma yiluphi uhlobo lomuthi, owengqondo noma ngenye indlela, ukuphathwa kwe-vilazodone kungaholela ochungechungeni lwemiphumela emibi engadingeki, kuye ngokuqina kanye nobude besikhathi ababhekana nayo, ingabacasula kakhulu.
Imiphumela engemihle ye-vilazodone ingahlukaniswa njengaleyo engabhekwa njengebucayi ngakho-ke ayidingi ukunakekelwa ngokushesha kwezokwelapha, kanye naleyo eyingozi kakhulu futhi edinga ukunakekelwa kwezokwelapha okuphuthumayo.
1. Imiphumela engemihle kakhulu
Imiphumela engemibi kakhulu yilena elandelayo.
- Isiyezi .
- Umlomo owomile
- Ukwanda kwesifiso sokudla
- Igesi kanye ne-flatulence.
- Isilungulela.
- Ukuzwa ubuhlungu noma ukunkenketha ezandleni noma ezinyaweni.
- ubuhlungu bamalunga .
- Ukuyaluza noma ukuzamazama okungalawuleki.
- Amaphupho okuqukethwe okungajwayelekile.
- Izinguquko esifisweni nasemandleni ocansi .
2. Imiphumela emibi kakhulu
Phakathi kwemiphumela emibi kakhulu ye-vilazodone, okulandelayo kuyagqama.
- Ukuphazamiseka kwesikhumba njengokuqubuka, ukuqubuka, noma amabala esikhumba.
- Ukuvuvukala
- Izinkinga zokuphefumula .
- Ukufiphala nokulahlekelwa ukwazi.
- Ukuquleka.
- Imfiva .
- Ukuphazamiseka kwenhliziyo, njengokushaya kwenhliziyo okusheshayo nokungajwayelekile.
- ukuqina kwemisipha okunzima .
- Uhudo
- Isicanucanu kanye/noma ukuhlanza .
- Ukopha ekhaleni
- Ukopha noma ukulimaza ngaphandle kwesizathu esibonakalayo.
- Ama-hallucinations.
- Ikhanda elibuhlungu .
- Izinkinga ngenkumbulo, ukugxilisa ingqondo noma ukusebenzisana.
- Ubuthakathaka bemisipha
- Ukunyakaza nokuwa okungajwayelekile.
Yiziphi izinyathelo zokuphepha okufanele zithathwe lapho uzisebenzisa?
Kuyadingeka ukuthi, ngaphambi kokuqala ukwelashwa nge-vilazodone, isiguli sazisa uchwepheshe wezokwelapha nganoma yiziphi izimo zezempilo ezikhethekile okuyo, kanye nokusetshenziswa kwanoma yiluphi olunye uhlobo lomuthi, ngencwadi noma ngaphandle kwencwadi kadokotela. Lokhu kuqapha kubaluleke kakhulu ezimeni zokwelashwa ngama-monoamine oxidase (MAO) inhibitors.
Ngaphezu kwalokho, isiguli kufanele futhi sazise uchwepheshe uma ehlushwa yinoma yikuphi ukungezwani komzimba noma uma ethatha noma yiluphi uhlobo lwe-vitamin supplement noma i-herbal complex yemvelo, njengoba lokhu kungase kuphazamise isenzo se-vilazodone.
Mayelana neziguli ezikhulelwe noma lapho uhlela ukukhulelwa ngesikhathi sokwelashwa, ukuphathwa kwe-vilazodone akukhuthazwa ngalesi sikhathi, ikakhulukazi ezinyangeni zokugcina zokukhulelwa, njengoba kuboniswe ukuthi kungabangela izinkinga ezinganeni ezisanda kuzalwa.
Okokugcina, i-vilazodone ingase ibangele umuzwa wobuthongo; ngakho-ke, lezo ziguli ezihlanganisa ukushayela noma ukusebenzisa imishini esindayo ohlelweni lwazo lwansuku zonke kufanele ziqaphele ngokukhethekile lezi zimpawu futhi, ngangokunokwenzeka, ziyeke le misebenzi ngesikhathi sokwelashwa.